Disease: Adenomatous Polyposis Coli
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZEB1 P37275 zinc finger E-box binding homeobox 1 Transcription factor 0.97 0.442 0.808
YWHAZ P63104 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta Chaperone 0.94 0.475 0.846
WNT2 P09544 Wnt family member 2 Signaling 1.8E-02 0.569 0.615
WIF1 Q9Y5W5 WNT inhibitory factor 1 Calcium-binding protein 1.3E-09 0.507 0.731
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
STAT6 P42226 signal transducer and activator of transcription 6 Nucleic acid binding 0.99 0.475 0.808
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
SGSM3 Q96HU1 small G protein signaling modulator 3 Enzyme 3.4E-15 0.469 0.808
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962
PYY P10082 peptide YY Signaling 1.2E-02 0.588 0.615
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
POLE Q07864 DNA polymerase epsilon, catalytic subunit 8.0E-27 0.526 0.731
POLD1 P28340 DNA polymerase delta 1, catalytic subunit 2.4E-06 0.507 0.769
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
PLK1 P53350 polo like kinase 1 Kinase 0.98 0.467 0.808
PLB1 Q6P1J6 phospholipase B1 1.7E-72 0.488 0.846